Xovoltib 30mg tablet| Afatinib Uses & Side effects

XOVOLTIB 30MG

DESCRIPTION

This is a phase 2 study that examines the performance of a cancer drug known as Xovoltib 30mg .
Xovoltib 30 mg  Tablets  prohibit EGFR protein, which accepts to be included in the growth management of chordoma tumors.
This study is planned especially for chordoma patients 18 years of age or older, with recurrent or metastatic tumors.
Xovoltib 30 mg which is used as a prescription drug under the guidance of the oncologist.

INDICATION

Xovoltib 30 mg  Tablets   is used for first-line treatment for patients with metastatic small cell lung cancer (NSCLC)

MECHANISM OF ACTION

The Afatinib mechanism by preventing the activity of a group of proteins known as epidermal growth factor receptors (EGFRs). The epidermal growth factor receptor is a protein that is included in the growth and spread of cancer cells; Afatinib works by inhibiting the action of this protein.
Afatinib should not be taken by people who have EGFR-negative tumors.

PRODUCT DETAILS

Brand: Xovoltib
Ingrediente: Afatinib
Power: 30mg
Fabricat: produse farmaceutice GSK
Pachet: 7 comprimate într-o bandă

Price: xovoltib 30mg price in india

Xovoltib 30mg

pharmacokinetics

• The maximum plasma time is 2-5 hours and the bioavailability is 92%
• Human plasma protein bound is 95%
• The main circulating metabolites are covalent adducts to proteins.
• Excretion of fecal drugs is 85% and urine 4%.

DOSAGE MANAGEMENT

For adults: 40 mg given once daily is the prescribed dose for adult patients with metastatic small cell lung cancer. The age of 0-17 years is not prescribed in children.
Avoid using Xovoltib 40 mg tablets under 18 years of age
The prescribed dose for renal failure is given 30 mg once daily

ADMINISTRATION

Administer  Xovoltib 30 mg  Tablets   on an empty stomach. Take Xovoltib 30mg 1 hour before or 2 hours after meals Avoid cutting or crushing the tablet

Overdose: Overdose is related to patients who have been consumed 360  Xovoltib 30 mg  Tablets  that cause nausea, vomiting, asthenia, abdominal pain and therefore have provided recovery measures for recovery.

PRECAUTIONS

Severe dehydration may occur with the use of Xovoltib 30mg . This can lead to severe or persistent diarrhea, vomiting or reduced fluid intake. Dehydration can lead to kidney failure, if severe enough. During treatment with this medicine, you may be encouraged to drink additional water.
During treatment with Xovoltib 30 mg tablets will lead to hepatotoxicity; monitor with regular liver testing; Withholding or stopping treatment for severe or worsening liver tests
The drug can lead to interstitial lung disease (ILD)
when given to pregnant women, Xovoltib 30mg will harm the fetus (embryo-fetal toxicity)
Discontinue if patients confirm with suspected keratitis or ulcerative keratitis
The  Xovoltib 30 mg  tablets  have high sunburn / phototoxicity; it can aggravate the rash or acne; Patients use caution to limit sun exposure and if sun protection and protective clothing.
sometimes, Xovoltib 30mg has been linked to corneal perforation, a serious injury to the part of the eye that focuses light on the eyes. If you have persistent eye pain or vision changes, inform your doctor immediately.

SIDE EFFECTS

Common side effects caused:
• Mild diarrhea for 1 day or less
• Decreased appetite
• Nausea and vomiting
• Oral ulcer
• Acne, itching, dry skin
• Red color, tenderness, swelling or other signs of infection around the nails or nails
Reacții adverse grave:
• Eye problems - blurred vision, watery eyes, increased light sensitivity
• Liver problems - stomach pain, sensation, dark urine
• Heart problems
• The color of the urine changes to dark
• Bleeding or bruising
• Weakness
• Blurry vision
• Fast heartbeat
• Breathing problems
• Cough and fever
• Yellowing of the skin

LAMMAL CANCER

DRUG INTERACTION

Co-administration of  Xovoltib 30 mg  Tablets  with P-gp inhibitors (cyclosporine A, ketoconazole verapamil) will have high exposure to Afatinib
When Xovoltib 30mg interaction with P-gp inducers (carbamazepine, phenytoin, phenobarbital) will decrease exposure to Afatinib

The dosage taken

If the patient missed the dose of Xovoltib 30 mg  Tablets  , then the missed dose should be skipped and follow the regular schedule. Do not administer the dose
Consult with your doctor and follow the suggestions.

PREGNANCY

Pregnancy category: c
During treatment with Xovoltib 30mg Pregnancy should be avoided because the medication 

Xovoltib 30 mg  Tablets  are given to a pregnant woman who will harm the unborn child.

breastfeeding

Xovoltib 30mg Excretion in human milk is not known or will have adverse reactions in a breast-fed child. Therefore, the decision can be made if you stop breastfeeding or discontinuing the drug.

STORAGE

•  Xovoltib 30 mg  Compress  25 ° C
• Keep Xovoltib 30mg for children
• Protect from moisture and light.

CONTACT US 

ID EMAIL:  millionhealthpharmaceuticals@gmail.com

TELEPHONE NR:  + 91-9940472902

WEB URL: https://millionpharma.com/xovoltib-30mg.php 

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