Reditux 500mg

REDITUX 500mg

DESCRIPTION

Reditux 500 mg is an antitumor drug that prevents the growth and spread of cancer cells in the body. Reditux 500 mg is also indicated for the treatment of non-Hodgkin lymphoma or chronic lymphocytes and in combination with other anti-cancer drugs, such as methotrexate, is used to treat symptoms of rheumatoid arthritis in adults.

Reditux 500 mg  Injection  with a combination of steroid regimens is intended to treat some rare diseases that cause inflammation of the blood vessels and other body tissues.

INDICATIONS

Reditux 500 mg and hyaluronidase for injection are administered to humans alone or in combination with other drugs to treat certain types of non-Hodgkin's lymphoma and chronic lymphocytic leukemia (cancer begins with WBC). Reditux 500 mg  Injection is  also used with methotrexate (Otrexup, Rasuvo, Xatmep, etc.) to treat the symptoms of rheumatoid arthritis in adults who have already been treated with some regimen known as tumor necrosis factor inhibitor (TNF). Reditux 500 mg is the type in the classification of drugs called monoclonal antibodies. Reditux 500 mg  Injection used to destroy cancer cells for the treatment of NHL, CLL, rheumatoid arthritis, granulomatosis with polyangiitis and microscopic polyangiitis by stopping the activity of that part of the immune system that damages joints, veins and other blood vessels and leads to damage to organs (heart and lungs).

Pharmacodynamic

A new type of “targeted” cancer treatment and an integral part of the body’s immune system. Naturally, the body produces antibodies along with the antigen that has entered the body and attaches to the antigen to be destroyed by the immune system. Essential cells that target monoclonal antibiotics only can reduce toxicity to healthy cells, and usually this treatment is only recommended for cancers in which antigens (and corresponding antibodies) have already been identified. Reditux 500 mg  Injection  works by binding to the CD20 antigen on normal and malignant B cells. Therefore, the body’s primary immune safety is triggered to attack and kill marked B cells.Stem cells are young cells in the bone marrow that will grow into cells of various types and lack the CD20 antigen. After treatment,

PRODUCT INFORMATION

Brand Reditux
Ingredients: Rituximab
Strength: 500 mg
Manufactured by: Dr. Reddy's
Package: Injection
Price: Reditux 500 mg price in India

Reditux 500mg

Pharmacokinetics

Absorption

Not available

SPREAD

volume of distribution 3.1 l

EXCHANGE

Reditux 500 mg  Injection is  metabolized by the production of human antibodies against murin.

EXCRETION

no data The half-life of NHL is 22 days, and with RA - 18.0 days, GPA and microscopic polyangitis - 23 days.

Dosage management

Reditux 500 mg  Injection   recommended  Reditux 500 mg is    only intravenous, not intravenous or bolus.

BEFORE EACH INFUSION PREFERENCE

First infusion: initially, the rate is 50 mg / hour, in the absence of toxicity during infusion, the rate increases to 50 mg / hour at intervals of 30 minutes and a maximum of 400 mg / hour. Sequential infusion: initial rate of 100 mg / hour, in the absence of toxicity during infusion, the rate increases to 100 mg / hour at intervals of 30 minutes and a maximum of 400 mg / hour. Corticosteroid premedication should be considered if

Reditux 500 mg   Combination Injection with CHOP Chemotherapy not available.

LOW VARIETY OR UNTREATED NIKHODGKIN LYMPHOMA

The dose is 375 mg / m2 as an intravenous infusion. Once a week for 4 or 8 doses given for relapse treatment. Previously untreated: up to 8 doses were administered on the 1st day of each chemotherapy cycle. For a complete or partial patient response, start at 8 weeks for a maintenance Reditux 500 mg  after  Reditux 500 mg  Injection  combined with completed chemotherapy, then prescribe 8 weeks for 12 doses as the only means. Once a week, 4 doses at intervals of 6 months and a maximum of 16 doses in the absence of progression (after completion of CVP chemotherapy after 6 to 8 cycles). On the first day of each chemotherapy cycle, up to 8 infusions with diffuse large B-cell NHL.

ZEVALIN COMPONENT FOR NHL TREATMENT

Prior to administration of indium-111- (In-111-) zevalin and yttrium-90- (Y-90-) zevalin, Reditux 500 mg is administered  .  Injection  mg / m2 for 4 hours prior to administration of rituxan and Y-90 zevalin Rituxan and B- 111-Zevalin 7–9 days.

CHRONIC LYMPHOCYTIC LEUKEMIA

Before starting chemotherapy with FC, the recommended dose is 375 mg / m2, then 500 mg / m2 on the 1st day of 2-6 cycles every 28 days.

RHEUMATOID ARTHRITIS

Reditux 500 mg is administered with a combination of methotrexate. Redux is administered in two doses of 500 mg intravenously for 2 weeks. When glucocorticoids are administered as methyl prednisolone, 500 mg IV. A follow-up course based on clinical evaluation should be prescribed every 24 weeks, but not earlier than every 16 weeks.

GRANULOMATOSIS POLYNGIT AND MICROSCOPIC POLANGYT

A dose of 375 mg / m2 for intravenous infusion is administered weekly once for 4 weeks. While treating the symptoms of severe vasculitis. This medicine should be started within 14 days before or with the start of  Reditux 500 mg  injection  and may continue during and after a 4-week course of treatment with Reditux 500 mg . Safety and not established for subsequent infusion.

CONTROL

Take the amount of Reditux 500 mg and  Reditux 500 mg  Injection  to a final concentration of 1 mg / ml to 4 mg / ml as an infusion (containing 0.9% Nacl or 5% dextrose in water). Carefully turn the bag over and mix the solution. Dispose of unused product left in the vial. OVERDOSAGE: If patients had a high dose of Reditux, contact the emergency department or the poison control help desk immediately. Please consult your doctor for further clarification.

Precautionary measures

Allergic Disease Against Reditux 500 mg  Injection  or any other medicine inform your doctor. Regarding your past history of prescription, over-the-counter drug use, vitamins and supplements, foods just tell your doctor. When using Reditux 500 mg, do not take vaccinations or immunizations without consulting your doctors. Avoid using Reditux 500 mg  Injection if you are pregnant. This will harm the unborn baby when using  Reditux 500 mg.  Injection use proper birth control to prevent pregnancy and at least 2 weeks after your treatment ends. Reditux 500 mg may affect the ability to have children in women. Tell your doctor if you are planning a pregnancy. It is not known Reditux 500 mg.  Injection  passes into breast milk; avoid breast-feeding during treatment with Reditux 500 mg .

SIDE EFFECTS

GENERAL EFFECTS

fever and chills (flu symptoms)

Less common side effects

Weakness; nausea; Headache; cough; dyspnae; pharyngitis

DRUG INTERACTION

Reditux 500 mg   Drug Injection Interaction has limited data available at this time. The combination with fludarabine or cyclophosphamide does not affect the pharmacokinetics in patients with CLL. The combination with methotrexate did not affect the pharmacokinetics.

CONTRAINDICATIONS

Reditux 500 mg  Injection  Hypersensitivity or mouse proteins. Active severe infectons in rheumatoid arthritis Uncontrolled heart disease.

PREGNANCY

Category C: Reditux 500 mg   Animal reproduction studies have shown adverse effects on the fetus. The drug does not have sufficient and well-controlled studies in people using the benefits of using the drug in pregnant women.

LACTATION

Reditux 500 mg  Injection  into human milk is unknown. Due to the fact that the drug belongs to a large protein molecule, no information is available. Women should not breast-feed during  Reditux 500 mg  Injection  treatment for Reditux 500 mg and 12 months after the last dose.

STORAGE 

Reditux 500 mg  Injection  Store at 2–3 ° C. Use the drug until the expiration date. Protected from direct sunlight. Do not freeze or shake. Keep out of the reach of children. Discard an unused drug by consulting your doctor or pharmacist.

Missed dose

Reditux 500 mg  Injection  If a dose is missed to be taken at that time, then it is sudden until the next dose of the dose, if time reaches the next dose, then skip the missed dose and continue and continue the usual schedule. Do not take 2 doses at the same time.

TO CONTACT US

EMAIL ID:  millionhealthpharmaceuticals@gmail.com

Number Phone :  + 91-9940472902

Website URL: https://millionpharma.com/reditux-500mg.php 

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